Title: Graduate Student
Email: c.kuhnline@gmail.com
2005 B.S. Investigative and Medical Sciences, B.A. Chemistry
St. Louis University, St. Louis, MO.
My project will focus on peptide analysis and blood brain barrier (BBB) transport. The effect of structural modifications, metabolism, and NO production on BBB transport of dynorphin peptides will be investigated using both conventional and microchip methods. Endogenously Dynorphin A-(1-17) (Dyn A) and its many metabolites function as natural ligands for kappa ( k )-opioid receptors. The importance of Dynorphin A, its analogs, and its metabolites has been of interest due to the therapeutic potential of these neuropeptides.This family of peptides is being investigated asa therapy for neuropathic pain as well as drug addiction.
I love dancing! When I actually get a spare minute I enjoy reading novels, watching movies, traveling to sunny places and just hanging out with friends and family.
