CHEM 711 Applied Electronics for Scientists (4). Lecture and laboratory course for chemists and other scientists or engineers with little or no background in electronics who need a working knowledge of electronic devices, circuits, and instruments; electronic principles; digital and analog systems in scientific instrumentation; signal conversion and optimization techniques. Prerequisite: CHEM 516 or the equivalent, one year of physics; limited enrollment, see instructor.

CHEM 716 Practicum in Facilitating Learning in the Chemistry Laboratory (1). The course provides discussions of the diverse group of undergraduates, the laboratory curriculum, and laboratory teaching strategies. Strategies to facilitate learning through interaction among students and between student and TA will be discussed. The course includes reading assignments, peer review, and instructor feedback of teaching performance of TAs. Students participate in class discussion once per week. Prerequisite: Permission of instructor.

CHEM 718 Mathematical Methods in Physical Sciences (3). Review of all complex variable theory; introduction to the partial differential equations of physics; Fourier analysis; and special functions of mathematical physics. (Same as PHSX 718.) Prerequisite: Two semesters of junior-senior mathematics.

CHEM 720 Bibliography of Chemistry (1). A course on the use of the library as a research tool and the study of bibliographic techniques of literature searching. Emphasis on the literature of chemistry. Prerequisite: Consent of department.

CHEM 731 Fundamentals and Methods of Analytical Chemistry (3). An introductory graduate level course in analytical chemistry, in which the principles of electrochemistry, spectroscopy, and separation science are utilized to solve analytical problems in inorganic, organic and biochemistry. Prerequisite: An undergraduate course in analytical chemistry, a year of organic chemistry, and a year of physical chemistry.

CHEM 737 Coordination and Organometallic Chemistry (3). An examination of the basic foundations of coordination chemistry and organometallic chemistry including symmetry methods, bonding, magnetism, and reaction mechanisms. Prerequisite: Two semesters of organic chemistry and one semester of physical chemistry in which quantum chemistry is introduced. The latter course may be taken concurrently with CHEM 737.

CHEM 740 Principles of Organic Reactions (3). A consideration of the structural features and driving forces that control the course of chemical reactions. Topics will include acid and base properties of functional groups; qualitative aspects of strain, steric, inductive, resonance, and solvent effects on reactivity; stereo-chemistry and conformations; an introduction to orbital symmetry control; basic thermodynamic and kinetic concepts; and an overview of some important classes of mechanisms. Prerequisite: Two semesters of undergraduate organic and one semester of physical chemistry or concurrent enrollment.

CHEM 742 Physical Organic Chemistry I (3). An examination of the methods used to probe the mechanisms of organic reactions and of the chemistry of some important reactive intermediates. Topics will include isotope effects, kinetics, linear free energy relationships, solvent effects, a continuing discussion of orbital symmetry, rearrangements, carbocations, carbanions, carbenes, radicals, excited states, and strained molecules. Prerequisite: CHEM 740.

CHEM 750 Quantum Chemistry and Spectroscopy (3). An introductory study of the application of quantum mechanics to atomic and molecular systems. Includes an introduction to the basic principles of quantum theory, description of electronic structure of atoms and molecules, and the foundations of spectroscopy. Contains a brief presentation of group theory and its applications to the analysis of molecular symmetry, spectra and structure. Prerequisite: Two semesters of physical chemistry.

CHEM 752 Statistical Thermodynamics (3). Thermodynamics and introduction to equilibrium statistical mechanics with emphasis on problems of chemical interest. The course consists of two roughly equal parts: 1) An advanced overview of the laws and concepts of thermodynamics with application to specific problems in phase and chemical equilibria and 2) An introduction to equilibrium statistical mechanics for both classical and quantum systems. Prerequisite: CHEM 750 or its equivalent.

CHEM 754 Chemical Kinetics and Dynamics (3). Chemical kinetics and introduction to chemical reaction dynamics. The course consists of two parts: 1) An advanced overview of chemical kinetics including reaction mechanisms and rate laws with applications to unimolecular and bimolecular reactions, catalysis, and energy transfer, and 2) An introduction to reaction rate theory including transition state theory, Marcus electron transfer theory, and collision theory. Prerequisite: CHEM 750 or its equivalent.

CHEM 763 Organic Synthesis I (3). A discussion of fundamental reactions for the formation of carbon-carbon bonds, oxidation, reduction, and functional group interchange. Prerequisite: CHEM 740.

CHEM 766 Spectroscopic Identification of Organic Compounds (3). The use of techniques such as infrared, nuclear magnetic resonance, and ultraviolet spectroscopy, and mass spectrometry for elucidating the structure of organic molecules. A lecture and workshop course. Prerequisite: CHEM 626 and CHEM 627, or CHEM 707.

CHEM 767 Advanced Laboratory Techniques for the Preparation and Purification of Compounds (3). A laboratory course that includes many of the important procedures and methods of organic and inorganic synthesis. Prerequisite: CHEM 627.

CHEM 775 Chemistry of the Nervous System (3). A study of the overall concept of central nervous system functioning. A brief introduction to neuroanatomy and neurophysiological techniques as well as a relatively detailed discussion of the chemistry of neurotransmitters is included. (Same as BIOL 775, MDCM 775, and P&TX 775.) Prerequisite: One year of undergraduate organic chemistry.

CHEM 801 Analytical Chemistry Colloquium (1). Review of important aspects of analytical chemistry not covered in the regular graduate courses.

CHEM 807 Inorganic Chemistry Colloquium (00-1). Review of important aspects of inorganic chemistry not covered in the regular courses.

CHEM 810 Physical Chemistry Colloquium (1). Colloquia on various topics of current interest are presented by students, faculty, and visiting scientists.

CHEM 811 Organic Chemistry Colloquium (1). Credit on presentation of colloquium.

CHEM 812 Chemical Seminar (1-2). Individual studies of certain advanced phases of chemistry not covered in the regular graduate courses.

CHEM 899 Master’s Thesis (1-10). Research work (either experimental or theoretical) in chemistry for students working toward the M.S. degree.

CHEM 901 Advanced Analytical Chemistry Colloquium (1). Review of important aspects of analytical chemistry not covered in the regular graduate courses. Open to advanced graduate students.

CHEM 902 Inorganic Preparations (2-4). A laboratory course covering a variety of advanced preparative techniques used in inorganic chemistry. Prerequisite: CHEM 737 or equivalent.

CHEM 903 Electrical Methods of Analysis (2). An advanced treatment of selected electroanalytical techniques and methodology. The theory is augmented by applied laboratory work. Prerequisite: CHEM 731 or its equivalent.

CHEM 904 Analytical Separations (3) An advanced treatment of analytical separations techniques. The theory of separation science will be augmented with discussion of practical aspects of instrumentation and experiment design. Prerequisite: CHEM 731 or permission of instructor.

CHEM 906 Advanced Topics in Inorganic Chemistry: _____ (2-3). A course covering various special topics in inorganic chemistry. An announcement of course content and prerequisites will be made at the end of the previous semester. This course may be taken more than once.

CHEM 907 Advanced Inorganic Chemistry Colloquium (1). Review of important aspects of inorganic chemistry not covered in regular courses. Open to advanced graduate students.

CHEM 908 Spectrochemical Methods of Analysis (3). Lecture and laboratory course; general concepts of encoding chemical information as electromagnetic radiation; major instrumental systems for decoding, interpretation, and presentation of the radiation signals; atomic emission, absorption, and fluorescence; ultraviolet, visible, infrared, and microwave absorption; molecular luminescence; scattering methods; mass spectrometry; magnetic resonance; automated spectrometric systems. Prerequisite: CHEM 731 and CHEM 750.

CHEM 910 Advanced Physical Chemistry Colloquium (1). Colloquia on various topics of current interest are presented by students, faculty, and visiting scientists. Open to advanced graduate students.

CHEM 911 Advanced Organic Chemistry Colloquium (1). Credit on presentation of a colloquium. Open to advanced graduate students.

CHEM 912 Advanced Chemical Seminar (1). Individual studies of certain advanced phases of chemistry not offered in the regular graduate courses. Open to advanced graduate students.

CHEM 913 Chemical Kinetics (2-3). A study of the rates of chemical reactions in terms of the classical collision theory, transition-state theory and introductory scattering theory. Topics from the mechanism of gas and liquid phase reactions, fast reactions in solutions, molecular and ionic beam reactions, photochemistry, and other areas of current interest will be discussed. Prerequisite: CHEM 752 or its equivalent.

CHEM 914 Computational Methods in Physical Sciences (3). Advanced computer applications in physical science. General discussion and illustration of problem organization and solution by numerical and other methods with examples from physics, astronomy, and other physical sciences. Students will design, write, validate, and document a computer program to solve a physical problem. (Same as ASTR 815 and PHSX 815.) Prerequisite: Six hours of computer science courses numbered 300 or above, and six hours of physics and/or astronomy courses numbered 300 or above.

CHEM 915 Intermediate Quantum Mechanics (3). The mathematical and physical principles of quantum chemistry, including vector spaces, operators and operator algebra, matrix theory, eigenvalue problems, postulates of quantum mechanics, the Schrodinger equation, angular momentum, approximation methods, and atomic and molecular systems. Prerequisite: CHEM 750 or its equivalent.

CHEM 916 Molecular Spectroscopy (3). Quantitative molecular spectroscopy and its chemical applications. The basic principles of the molecular energy levels, selection rules and spectral transition intensities, and spectral interpretation will be discussed and applied to nuclear and electron magnetic resonance, rotational, vibrational, vibration-rotation, Raman, electronic and Mossbauer spectroscopy. Prerequisite: CHEM 750 or its equivalent.

CHEM 917 Advanced Statistical Mechanics (3). Advanced equilibrium statistical mechanics and introduction to nonequilibrium statistical mechanics. Topics include: the theory of liquids, critical phenomena linear response theory and time correlation functions, Langevin dynamics, and molecular hydrodynamics. (Same as PHSX 971.) Prerequisite: CHEM 909 or equivalent.

CHEM 918 Advanced Quantum Mechanics (3). An advanced discussion of the principles and methods of quantum mechanics and recent development of quantum chemistry, including subjects such as ab initio atomic and molecular structure calculations, quantum scattering theories, quantum optics, Lie group theoretical methods, and advanced numerical methods for solving the time-dependent Schrodinger equation. Prerequisite: CHEM 915 or its equivalent.

CHEM 919 Advanced Topics in Physical Chemistry: _____ (1-3). A discussion of special topics such as group theory, chemical bonding theory, microwave spectroscopy, electron paramagnetic resonance, mass spectrometry, X-ray crystallography, nuclear chemistry, radiation chemistry, high temperature chemistry, biophysical chemistry, irreversible thermodynamics, transport phenomena, scattering theory, etc. One or more topics will be covered in a given semester and an announcement of the course content and prerequisites will be made at the end of the previous semester. This course may be taken more than once.

CHEM 920 Mass Spectrometry (3) An introduction to mass spectrometry. The various ionization techniques and mass analyzers will be discussed, and many examples of different mass spectrometric applications will be introduced. Prerequisite: CHEM 731 or permission of instructor.

CHEM 925 Bioanalysis (3) A course covering important aspects in modern chemical measurement with particular emphasis placed on bioanalysis. This course will survey the modern analytical challenges associated with the ongoing efforts in genomics and proteomics and discuss future trends in methods and instrumentation. Prerequisite: CHEM 731 or permission of instructor.

CHEM 959 Advanced Topics in Analytical Chemistry: _____ (3). A course covering special advanced topics in analytical chemistry not included in other graduate courses. An announcement of course con-tent and prerequisites will be made at the end of the previous semester. This course may be taken more than once.

CHEM 963 Organic Synthesis II (3). A survey of important techniques in organic chemistry with respect to scope, limitations, mechanism, and stereochemistry. Emphasis will be placed on new synthetic methods and application of such methods to the synthesis of structurally interesting compounds, particularly natural products. Prerequisite: CHEM 763. 00 19 07 CHEM 966 Physical Organic Chemistry II (3). A detailed consideration of the mechanistic features of some important classes of organic reactions. Discussions will include an examination of molecular orbital theory, linear free energy relationships, and acid-base catalysis. Pre-requisite: CHEM 742 and one semester of physical chemistry.

CHEM 966 Physical Organic Chemistry II (3). A detailed consideration of the mechanistic features of some important classes of organic reactions. Discussions will include an examination of molecular orbital theory, linear free energy relationships, and acid-base catalysis. Prerequisite: CHEM 742 and one semester of physical chemistry.

CHEM 971 Introduction to Chemical Biology (3). Chemical biology is a multidisciplinary science where the knowledge of chemistry is utilized to solve problems in biology, and biological systems are evolved to gain new functions. This course aims to establish a great opportunity for graduate students at the interface of biology and chemistry.
The course will be a comprehensive introduction to chemical biology that covers both basics and cutting edge discoveries including:
1. fundamentals: structures and functions of natural molecules (i.e. nucleic acids, proteins, sugars, lipids), protein synthesis, post-translational modifications
2. techniques: recombinant DNA technology chemical approaches to study protein functions (mutagenesis, foldamer, unnatural amino acid incorporation, solid phase peptide synthesis, non-ribosomal peptide synthesis), molecular evolution, genomics and proteomics.
3. mechanistic study: enzymology and model systems
4. chemical biology applications: bio-imaging (GFP, metal detection), nucleic acid catalysis, inteins, catalytic antibodies, cell surface glycoproteins, engineered polyketide synthases, DNA-template synthesis

There is no required textbook, instead reference papers will be provided along with handouts.  Lectures are given mostly as a powerpoint presentation. Electronic version of lecture notes, course materials and links to useful web pages will be available through Blackboard.

CHEM 981 Research (1-10). Original investigation on the graduate level. Prerequisite: Forty hours of chemistry including appropriate preparation in the field of specialization.

CHEM 982 Inorganic Structure and Mechanisms (3). The use of quantum theory and group theory in interpreting bonding and physical and chemical properties in inorganic compounds. Mechanistic aspects of transition metal chemistry including substitution reactions, electron transfer reactions, rearrangement reactions, ligand reactions and inorganic photochemistry. Prerequisite: CHEM 737.

CHEM 984 Physical Methods (3). A survey of modern spectroscopic and non-spectroscopic physical methods in chemistry with emphasis on methods applicable to inorganic compounds. For each method, a brief introduction to underlying theoretical principles will be given and examples of applications from the literature will be discussed in detail. Prerequisite: CHEM 982.

CHEM 986 Bioinorganic and Catalytic Chemistry (3). A survey of metalloproteins and metalloenzymes and their structures and functions, including recent advances in biomimetic modeling. Principles and applications of heterogeneous and homogeneous catalytic processes emphasizing catalysis at transition metal centers.

CHEM 991 Postdoctoral Research in Chemistry (1-3). Advanced level research in collaboration with a faculty member involving projects in chemistry or related areas. Prerequisite: Doctoral degree or equivalent in an appropriate related area and consent of instructor.

CHEM 999 Doctoral Dissertation (1-10). Research work (either experimental or theoretical) in chemistry for students working toward the Ph.D. degree.