K. Barbara Schowen

Academic Degrees

• B.A., 1960, Wellesley College
• Ph.D., 1964, Massachusetts Institute of Technology

Areas of Specialization

Solvent Effects on Mechanisms of Enzyme-Catalyzed Reactions

Research Interests

Organic chemistry: bioorganic reaction mechanisms, enzymic and proton-transfer catalysis, solvent effects, solvent isotope effects.

Selected publications

Tian, J.; Tan, J.; Schowen, K.B. and Schowen, R.L., "The Role of the Medium in Solvent Isotope Effects on Serine Protease Action," Can. J. Chem., 1999, 77, 781-786.

Schowen, K.B.; Limbach, H.-H.; Denisov, G.S. and Schowen, R.L., "Hydrogen bonds and proton transfer in general-catalytic transition-state stabilization in enzyme catalysis," Biochimica et Biophysica Acta, 2000 1458, 43-62.